KEGG   REACTION: R03325
Entry
R03325                      Reaction                               
Name
17alpha,20alpha-dihydroxypregn-4-en-3-one:NADP+ 20-oxidoreductase
Definition
17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
Equation
C04518 + C00006 <=> C01176 + C00005 + C00080
Comment
NAD+ (see R03324)
Reaction class
RC00001  C00005_C00006
RC00228  C01176_C04518
Enzyme
1.1.1.149
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149
     R03325  17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
Other DBs
RHEA: 15860

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (98)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (96)   
All databases (110)   

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